03-05-2023 : 769 Pharmacists work as Medical Representative, of which 39 work as Senior Medical Representative * 02-06-2020 : 216 non Pharmacists work as Medical Representative, and 54 work as Senior Medical Representative * 05-06-2023 : In Lebanon, 88 generic medicinal products are more expensive than their Originators * 31-12-2019 : A medicinal product refused in Europe is marketed in Lebanon * 05-06-2023 : At least 332 medicinal products are available on the Lebanese market and are not available in the country of origin * 05-06-2023 : The price of the most expensive medicine available in Lebanon is 30434557 LL * 05-06-2023 : At least 1309 medicinal products are more expensive in Lebanon than in the countries of origin * 01-01-2019 : Daktavira, a generic of Daklinza, is registered in Lebanon but has no public price * 31-12-2019 : 352 medicinal products have been declared as non-marketed or withdrawn * 09-11-2021 : 64.72% of lebanese pharmacists are female * 31-12-2019 : 486 medicines were submitted to the Ministry of Health for a marketing authorization, and 514 medicines were registered to date * 15-06-2018 : The Minister of Public Health, has decided to suspend the commercialization of AB Slim (Ab Care Medical Herbs), which contains sibutramine, sildenafil and phenolphthalein * 01-06-2020 : Some Non-Marketed medicines are still imported * 01-06-2020 : Ixempra, a medicinal product withdrawn in Europe is imported to lebanon * 01-06-2020 : A vaccine made in India, removed from WHO list of prequalified vaccines, is submitted for registration in Lebanon * 01-06-2020 : Lebanon has 14 CROs, and is ranked as one of the largest countries in the world in clinical studies. According to the WHO, 817 clinical studies are currently conducted in Lebanon. * 05-01-2021 : * 01-10-2023 : Adakveo is now withdrawn from use in the European Union due to lack of therapeutic efficacy *
Erwinase° : | |
Type | Medicine Withdrawn |
Originator | Biotech (Kidrolase) |
Agent | BroadMed |
Distributor | BroadMed |
Laboratory | Jazz Pharmaceuticals |
Responsible Party | Jazz Pharmaceuticals |
Origin | France |
Manufacturer | Porton Biopharma |
Origin | UK |
ATC | L01XX02 |
Erwinase° :
Erwinase° :
Erwinase° :
Erwinase° :
Erwinase° :
Hazard Level |
---|
◼ Major |
◼ Moderate |
◼ Minor |
◼ Safe |
Erwinase° :
Frequency | Percentage |
---|---|
Very Common | ≥ 1/10 |
Common | ≥ 1/100 - < 1/10 |
Uncommon | ≥ 1/1,000 - < 1/100 |
Rare | ≥ 1/10,000 - < 1/1,000 |
Very Rare | < 1/10,000 |
Unknown | Cannot be Estimated |
Effect | Frequency |
---|---|
Abdominal pain | Not known |
Abnormal clotting factor | Very Common |
Alkaline phosphatase serum increased | Common |
ALT increased | Common |
Anaphylaxis | Uncommon |
Antithrombin III decreased | Very Common |
Arthritis reactive | Very rare |
AST increased | Common |
Bleeding | Common |
Blood bilirubin increased | Common |
Bronchospasm | Uncommon |
Chills | Common |
Cholesterol serum elevated | Common |
CNS depression | Rare |
Coagulation disorders | Very Common |
Coagulopathy | Common |
Coma | Rare |
Confusion | Common |
Convulsion | Common |
Diabetic ketoacidosis | Rare |
Diarrhoea (Diarrhea) | Common |
Dizziness | Common |
Dysphagia | Rare |
Dysphasia | Rare |
Dyspnoea (dyspnea) | Common |
Encephalopathy | Rare |
Erythema | Common |
Face oedema | Common |
Febrile neutropenia (Neutropenic fever) | Very rare |
Fibrinogen decreased | Very Common |
Flushing | Not known |
Grand mal convulsion | Common |
Haemorrhage | Not known |
Headache | Common |
Hepatic failure (Hepatic insufficiency) (Liver failure) | Rare |
Hepatomegaly | Not known |
Hepatotoxicity (liver toxicity) | Common |
Hyperammonaemia | Not known |
Hyperglycaemia | Uncommon |
Hyperlipidaemia | Uncommon |
Hypersensitivity reactions | Common |
Hypertension | Not known |
Hypofibrinogenaemia | Common |
Hypotension | Not known |
Hypoxia | Uncommon |
Infection | Very rare |
Injection site erythema | Common |
Injection site pain | Common |
Injection site reaction | Common |
Injection site swelling | Common |
Jaundice cholestatic (Cholestatic icterus) | Not known |
Laryngeal oedema | Uncommon |
Lethargy | Common |
Lip swelling | Common |
Lipase increased | Common |
Myalgia | Very rare |
Myocardial infarction | Rare |
Nausea | Not known |
Necrotizing pancreatitis | Very rare |
Neurotoxicity | Common |
Neutropenia | Very rare |
Pain | Common |
Pain in extremity (Pain in limb) | Common |
Pallor | Common |
Pancreatitis | Rare |
Pancreatitis acute | Common |
Pancreatitis haemorrhagic | Very rare |
Paresis | Rare |
Partial seizures | Common |
Posterior reversible leukoencephalopathy syndrome (PRES) | Rare |
Protein C deficiency | Very Common |
Protein S decreased | Very Common |
Pruritus | Common |
Purpura | Common |
Pyrexia | Common |
Respiratory arrest | Uncommon |
Rhinitis | Uncommon |
Sepsis (Systemic infection) (Sepsis state) | Very rare |
Serum amylase increased | Common |
Skin rash | Common |
Somnolence | Common |
Swelling of limb | Common |
Systemic allergic reaction | Common |
Thrombocytopenia (Thrombopenia) | Very rare |
Thrombosis | Rare |
Thrombotic events | Common |
Urticaria | Common |
Vomiting | Not known |
NB : Products With Same Indication |
Different Units By MoH Code
Erwinase° MoH 5707 :
Form | Powder for solution for injection |
Packaging | Bottle (Glass) |
Package Size | 5x3ml |
Strength | 10000IU |
NSSF | ✘ |
Quarantine | ✔ |
Reg. Number | 219271/09 |
Submission date | 01/01/2009 |
Registration Year | 2010 |
Archived Date | 08/04/2022 |
Withdrawn Date | 05/09/2023 |
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