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03-05-2023 : 769 Pharmacists work as Medical Representative, of which 39 work as Senior Medical Representative * 02-06-2020 : 216 non Pharmacists work as Medical Representative, and 54 work as Senior Medical Representative * 05-06-2023 : In Lebanon, 88 generic medicinal products are more expensive than their Originators * 31-12-2019 : A medicinal product refused in Europe is marketed in Lebanon * 05-06-2023 : At least 332 medicinal products are available on the Lebanese market and are not available in the country of origin * 05-06-2023 : The price of the most expensive medicine available in Lebanon is 30434557 LL * 05-06-2023 : At least 1309 medicinal products are more expensive in Lebanon than in the countries of origin * 01-01-2019 : Daktavira, a generic of Daklinza, is registered in Lebanon but has no public price * 31-12-2019 : 352 medicinal products have been declared as non-marketed or withdrawn * 09-11-2021 : 64.72% of lebanese pharmacists are female * 31-12-2019 : 486 medicines were submitted to the Ministry of Health for a marketing authorization, and 514 medicines were registered to date * 15-06-2018 : The Minister of Public Health, has decided to suspend the commercialization of AB Slim (Ab Care Medical Herbs), which contains sibutramine, sildenafil and phenolphthalein * 01-06-2020 : Some Non-Marketed medicines are still imported * 01-06-2020 : Ixempra, a medicinal product withdrawn in Europe is imported to lebanon * 01-06-2020 : A vaccine made in India, removed from WHO list of prequalified vaccines, is submitted for registration in Lebanon * 01-06-2020 : Lebanon has 14 CROs, and is ranked as one of the largest countries in the world in clinical studies. According to the WHO, 817 clinical studies are currently conducted in Lebanon. * 05-01-2021 : * 01-10-2023 : Adakveo is now withdrawn from use in the European Union due to lack of therapeutic efficacy *

Products » Items » Tykerb


Contraindicated
Reproductive toxicity in animals

Contraindicated
Tykerb :
Type Medicine Authorised
Originator B
Agent Khalil Fattal & Fils
Distributor Khalil Fattal & Fils
Laboratory Novartis
Responsible Party Novartis Pharma AG
Origin Switzerland
Manufacturer
Origin Roumania
ATC L01EX07
Revision Date 30/09/2013

Your comment will appear shortly after approval

Tykerb :

Revision Date : 19/06/2015


Effect Frequency
Abdominal pain Very Common
Alopecia Very Common
Anaphylaxis Rare
Anorexia Very Common
Arthralgia (Pain joint) (Joint ache) Very Common
Asthenia Very Common
Back pain Very Common
Cardiac failure Not known
Constipation Very Common
Cough Very Common
Dehydration Very Common
Dermatitis acneiform Very Common
Diarrhoea (Diarrhea) Very Common
Drug-induced hepatotoxicity Not known
Dry skin Very Common
Dyspepsia Very Common
Dyspnoea (dyspnea) Very Common
Epistaxis (Nasal bleeding) Very Common
Fatigue Very Common
Hand and foot syndrome (Palmar-plantar erythrodysaesthesia syndrome) Very Common
Headache Very Common
Hepatotoxicity (liver toxicity) Common
Hot flush Very Common
Hyperbilirubinaemia Common
Hypersensitivity reactions Rare
Insomnia Very Common
Interstitial pneumonitis Uncommon
Left ventricular ejection fraction decreased Common
Mucosal inflammation Very Common
Nail disorders Common
Nausea Very Common
Pain in extremity (Pain in limb) Very Common
Palpitations Not known
Paronychia Common
Pneumonitis Uncommon
Pruritus Very Common
QT interval prolonged (QT prolongation) Not known
Renal failure acute (Acute renal insufficiency) (Kidney failure acute) (Renal insufficiency acute) Not known
Skin rash Very Common
Skin reaction Not known
Stomatitis Very Common
Vomiting Very Common

Different Units By MoH Code

Revision Date : 01/12/2018

Revision Date : 07/03/2022

Tykerb  MoH 10824 :
Form Tablet, Film-Coated
Packaging Bottle (HDPE) (high density polyethylene)
Package Size Box of 70
Strength 250mg
Public Price 101971611.34 L.L.
Stratum E2
NSSF ✔
Quarantine ✔
Reg. Number 130016/1
Submission date 2022
Registration Year 06/06/2022


NB : Reregistration in 2022 with different manufacturer

Price Comparison

● Country: Tunisia
● Package Size: Boîte de 70
● Public Price: 10971 TND ( 316,677,915.00 LBP )
● Pack size unit used: 70
● Cost/Unit: 156,7286 TND ( 4,502,940.00 LBP )
● Pricing Date: 04/02/2019
● Type: Medicine Authorised

● Country: Greece
● Package Size: 150
● Public Price: 4228.44 EUR ( 409,634,353.44 LBP )
● Pack size unit used: 150
● Cost/Unit: 28,1896 EUR ( 2,712,528.00 LBP )
● Reference: National Organization for Medicines
● Pricing Date: 25/03/2019
● Type: Medicine Non Marketed

● Country: Italy
● Package Size: 70
● Public Price: 1824.63 EUR ( 176,762,855.88 LBP )
● Pack size unit used: 70
● Cost/Unit: 26,0661 EUR ( 2,518,776.00 LBP )
● Exfactory Price: 1105.56 EUR
● Medica Comments: Tyverb = Tykerb
● Pricing Date: 17/12/2019
● Type: Medicine Authorised

● Country: Qatar
● Package Size: 70
● Public Price: 6462 QAR ( 158,693,796.00 LBP )
● Pack size unit used: 70
● Cost/Unit: 92,3143 QAR ( 2,259,336.00 LBP )
● Pharmacy Price: 5307.98498984 QAR ( 130353495.38049 LBP )
● Pricing Date: 28/01/2021
● Type: Medicine Authorised

● Country: Germany
● Package Size: 70
● Public Price: 1679.07 EUR ( 162,661,585.32 LBP )
● Pack size unit used: 70
● Cost/Unit: 23,9867 EUR ( 2,228,148.00 LBP )
● Pricing Date: 24/10/2020
● Type: Medicine Authorised

● Country: Abu Dhabi
● Package Size: 70s (10s Blister x 7)
● Public Price: 6038 AED ( 145,884,118.00 LBP )
● Pack size unit used: 70
● Cost/Unit: 86,2571 AED ( 2,077,846.00 LBP )
● Pharmacy Price: 5143.78 AED ( 124278868.58 LBP )
● Pricing Date: 27/01/2021
● Type: Medicine Authorised

● Country: UAE
● Package Size: 70's (10's Blister x 7)
● Public Price: 6038 AED ( 145,884,118.00 LBP )
● Pack size unit used: 70
● Cost/Unit: 86,2571 AED ( 2,077,846.00 LBP )
● Pharmacy Price: 5143.78 AED ( 124278868.58 LBP )
● Pricing Date: 21/08/2019
● Type: Medicine Authorised

● Country: Oman
● Package Size: 70
● Public Price: 680.37 OMR ( 156,984,491.58 LBP )
● Pack size unit used: 70
● Cost/Unit: 9,7196 OMR ( 2,076,606.00 LBP )
● Pricing Date: 19/02/2021
● Type: Medicine Authorised

● Country: Kuweit
● Package Size: Boîte de 70
● Public Price: 530.16 KWD ( 155,644,902.96 LBP )
● Pack size unit used: 70
● Cost/Unit: 7,5737 KWD ( 2,055,067.00 LBP )
● Pharmacy Price: 447.89 KWD ( 131491994.09 LBP )
● Pricing Date: 07/02/2021
● Type: Medicine Authorised

● Country: Switzerland
● Package Size: 70
● Public Price: 1394.45 CHF ( 144,214,019.00 LBP )
● Pack size unit used: 70
● Cost/Unit: 19,9207 CHF ( 1,964,980.00 LBP )
● Exfactory Price: 1215.38 CHF
● Medica Comments: Tyverb = Tykerb
● Pricing Date: 04/04/2021
● Type: Medicine Authorised

● Country: Bahrain
● Package Size: 70
● Public Price: 572.96 BHD ( 136,212,072.64 LBP )
● Pack size unit used: 70
● Cost/Unit: 8,1851 BHD ( 1,901,872.00 LBP )
● Reference: nhra
● Pricing Date: 09/02/2021
● Type: Medicine Authorised

● Country: Finland
● Package Size: 70
● Public Price: 1388.33 EUR ( 134,495,857.08 LBP )
● Pack size unit used: 70
● Cost/Unit: 19,8333 EUR ( 1,840,644.00 LBP )
● Medica Comments: Tyverb = Tykerb
● Reference: Kela
● Pricing Date: 22/04/2021
● Type: Medicine Authorised

● Country: Iceland
● Package Size: 84
● Public Price: 229983 ISK ( 148,339,035.00 LBP )
● Pack size unit used: 84
● Cost/Unit: 2737,8929 ISK ( 1,765,365.00 LBP )
● Pharmacy Price: 179808 ISK ( 115976160 LBP )
● Medica Comments: Tyverb = Tykerb
● Reference: Icelandic Medicines Agency
● Pricing Date: 01/04/2020
● Type: Medicine Authorised

● Country: Belgium
● Package Size: 140
● Public Price: 2454 EUR ( 237,733,704.00 LBP )
● Pack size unit used: 140
● Cost/Unit: 17,5286 EUR ( 1,646,892.00 LBP )
● Medica Comments: Tyverb = Tykerb
● Reference: cbip
● Pricing Date: 02/12/2020
● Type: Medicine Authorised

● Country: The Netherlands
● Package Size: 70
● Public Price: 1249.11 EUR ( 121,008,780.36 LBP )
● Pack size unit used: 70
● Cost/Unit: 17,8444 EUR ( 1,646,892.00 LBP )
● Pharmacy Price: 1242.11 EUR ( 120330648.36 LBP )
● Reference: Zorginstituut Nederland
● Pricing Date: 15/06/2019
● Type: Medicine Authorised

● Country: Jordan
● Package Size: 70
● Public Price: 920.17 JOD ( 115,224,607.57 LBP )
● Pack size unit used: 70
● Cost/Unit: 13,1453 JOD ( 1,627,873.00 LBP )
● Pharmacy Price: 884.78 JOD ( 110793036.38 LBP )
● Reference: JFDA
● Pricing Date: 02/01/2021
● Type: Medicine Authorised

● Country: Ireland
● Package Size: 70
● Public Price: 1161.76 EUR ( 112,546,661.76 LBP )
● Pack size unit used: 70
● Cost/Unit: 16,5966 EUR ( 1,550,016.00 LBP )
● Medica Comments: Tyverb = Tykerb
● Pricing Date: 08/10/2020
● Type: Medicine Authorised

● Country: France
● Package Size: 70
● Public Price: 1155.42 EUR ( 111,932,467.92 LBP )
● Pack size unit used: 70
● Cost/Unit: 16,506 EUR ( 1,550,016.00 LBP )
● Medica Comments: Tyverb = Tykerb
● Reference: ansm
● Pricing Date: 15/05/2021
● Type: Medicine Authorised

● Country: Cyprus
● Package Size: 70 TABS
● Public Price: 1160.72 EUR ( 112,445,910.72 LBP )
● Pack size unit used: 70
● Cost/Unit: 16,5817 EUR ( 1,550,016.00 LBP )
● Medica Comments: Tyverb = Tykerb
● Reference: Cyprus Minister of Health
● Pricing Date: 24/03/2021
● Type: Medicine Authorised

● Country: KSA
● Package Size: 70
● Public Price: 4499.75 SAR ( 106,374,090.00 LBP )
● Pack size unit used: 70
● Cost/Unit: 64,2821 SAR ( 1,512,960.00 LBP )
● Reference: sfda
● Pricing Date: 16/01/2021
● Type: Medicine Authorised

● Country: Lebanon
● Form: Tablet, Film-Coated
● Package Size: Box of 70
● Public Price: 101971611.34 LBP ( 101,971,611.34 LBP )
● Pack size unit used: 70
● Cost/Unit: 1456737,3 LBP ( 1,456,737.00 LBP )
● Pricing Date: 03/09/2026

● Country: Spain
● Package Size: 140
● Public Price: 2167.89 EUR ( 210,016,511.64 LBP )
● Pack size unit used: 140
● Cost/Unit: 15,4849 EUR ( 1,453,140.00 LBP )
● Reference: Agencia Española de Medicamentos y Productos Sanitarios
● Pricing Date: 06/05/2021
● Type: Medicine Authorised

● Country: Czech Republic
● Package Size: 70
● Public Price: 26588.91 CZK ( 101,543,047.29 LBP )
● Pack size unit used: 70
● Cost/Unit: 379,8416 CZK ( 1,447,401.00 LBP )
● Medica Comments: Tyverb = Tykerb
● Reference: SUKL
● Pricing Date: 28/02/2020
● Type: Medicine Authorised

● Country: Sweden
● Package Size: 70
● Public Price: 11788.49 SEK ( 99,117,623.92 LBP )
● Pack size unit used: 70
● Cost/Unit: 168,407 SEK ( 1,412,544.00 LBP )
● Pharmacy Price: 11512 SEK ( 96792896 LBP )
● Medica Comments: Tyverb = Tykerb
● Pricing Date: 23/04/2020
● Type: Medicine Authorised

● Country: UK
● Package Size: 70
● Public Price: 804.3 GBP ( 91,407,890.70 LBP )
● Pack size unit used: 70
● Cost/Unit: 11,49 GBP ( 1,250,139.00 LBP )
● Medica Comments: Tyverb = Tykerb
● Reference: DMD
● Pricing Date: 08/03/2021
● Type: Medicine Withdrawn

● Country: Norway
● Package Size: 70
● Public Price: 10785.9 NOK ( 87,408,933.60 LBP )
● Pack size unit used: 70
● Cost/Unit: 154,0843 NOK ( 1,248,016.00 LBP )
● Pharmacy Price: 8431.1 NOK ( 68325634.4 LBP )
● Medica Comments: Tyverb = Tykerb
● Reference: Norwegian Medicine Agency
● Pricing Date: 01/04/2020
● Type: Medicine Withdrawn

● Country: Egypt
● Package Size: Boîte de 70
● Public Price: 6016 EGP ( 10,979,200.00 LBP )
● Pack size unit used: 70
● Cost/Unit: 85,9429 EGP ( 155,125.00 LBP )
● Pricing Date: 02/12/2019
● Type: Medicine Authorised

● Country: Turkey
● Package Size: 70
● Public Price: 3974.44 TRY ( 10,651,499.20 LBP )
● Pack size unit used: 70
● Cost/Unit: 56,7777 TRY ( 150,080.00 LBP )
● Pricing Date: 28/10/2020
● Type: Medicine Authorised

● Country: New Zealand
● Package Size: 70 tab
● Exfactory Price: 1899 NZD
● Reference: New Zealand Pharmaceutical Management Agency
● Pricing Date: 01/04/2020
● Type: Medicine Authorised

● Country: Denmark
● Package Size: 70
● Medica Comments: Tyverb = Tykerb
● Reference: Danish Medicine Agency
● Pricing Date: 19/05/2021
● Type: Medicine Non Marketed

    ◼ Lebanon
    ◼ Country of Origin
    ◼ Reference Countries
    ◼ Other Countries

Note

Breast cancer : (Adults)
● Cost/Unit: 156,7286 TND ( 4,502,940.00 LBP )
● Cost/Day: 783,64 TND ( 22,601,295.00 LBP )
● Cost/Month: 23509,2 TND ( 678,587,285.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 28,1896 EUR ( 2,712,528.00 LBP )
● Cost/Day: 140,95 EUR ( 13,562,640.00 LBP )
● Cost/Month: 4228,5 EUR ( 409,591,728.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 26,0661 EUR ( 2,518,776.00 LBP )
● Cost/Day: 130,33 EUR ( 12,593,880.00 LBP )
● Cost/Month: 3909,9 EUR ( 378,688,284.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 92,3143 QAR ( 2,259,336.00 LBP )
● Cost/Day: 461,57 QAR ( 11,321,238.00 LBP )
● Cost/Month: 13847,1 QAR ( 340,054,626.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 23,9867 EUR ( 2,228,148.00 LBP )
● Cost/Day: 119,93 EUR ( 11,528,244.00 LBP )
● Cost/Month: 3597,9 EUR ( 348,462,972.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 86,2571 AED ( 2,077,846.00 LBP )
● Cost/Day: 431,29 AED ( 10,413,391.00 LBP )
● Cost/Month: 12938,7 AED ( 312,595,018.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 86,2571 AED ( 2,077,846.00 LBP )
● Cost/Day: 431,29 AED ( 10,413,391.00 LBP )
● Cost/Month: 12938,7 AED ( 312,595,018.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 9,7196 OMR ( 2,076,606.00 LBP )
● Cost/Day: 48,6 OMR ( 11,075,232.00 LBP )
● Cost/Month: 1458 OMR ( 336,410,172.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 7,5737 KWD ( 2,055,067.00 LBP )
● Cost/Day: 37,87 KWD ( 10,862,497.00 LBP )
● Cost/Month: 1136,1 KWD ( 333,508,016.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 19,9207 CHF ( 1,964,980.00 LBP )
● Cost/Day: 99,6 CHF ( 10,238,580.00 LBP )
● Cost/Month: 2988 CHF ( 309,018,960.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 8,1851 BHD ( 1,901,872.00 LBP )
● Cost/Day: 40,93 BHD ( 9,509,360.00 LBP )
● Cost/Month: 1227,9 BHD ( 291,699,618.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 19,8333 EUR ( 1,840,644.00 LBP )
● Cost/Day: 99,17 EUR ( 9,590,724.00 LBP )
● Cost/Month: 2975,1 EUR ( 288,206,100.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 2737,8929 ISK ( 1,765,365.00 LBP )
● Cost/Day: 13689,46 ISK ( 8,829,405.00 LBP )
● Cost/Month: 410683,8 ISK ( 264,890,535.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 17,5286 EUR ( 1,646,892.00 LBP )
● Cost/Day: 87,64 EUR ( 8,428,212.00 LBP )
● Cost/Month: 2629,2 EUR ( 254,687,004.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 17,8444 EUR ( 1,646,892.00 LBP )
● Cost/Day: 89,22 EUR ( 8,621,964.00 LBP )
● Cost/Month: 2676,6 EUR ( 259,240,176.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 13,1453 JOD ( 1,627,873.00 LBP )
● Cost/Day: 65,73 JOD ( 8,139,365.00 LBP )
● Cost/Month: 1971,9 JOD ( 246,810,591.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 16,5966 EUR ( 1,550,016.00 LBP )
● Cost/Day: 82,98 EUR ( 7,943,832.00 LBP )
● Cost/Month: 2489,4 EUR ( 241,124,364.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 16,5817 EUR ( 1,550,016.00 LBP )
● Cost/Day: 82,91 EUR ( 7,943,832.00 LBP )
● Cost/Month: 2487,3 EUR ( 240,930,612.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 16,506 EUR ( 1,550,016.00 LBP )
● Cost/Day: 82,53 EUR ( 7,943,832.00 LBP )
● Cost/Month: 2475,9 EUR ( 239,768,100.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 64,2821 SAR ( 1,512,960.00 LBP )
● Cost/Day: 321,41 SAR ( 7,588,440.00 LBP )
● Cost/Month: 9642,3 SAR ( 227,936,880.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 1456737,3 LBP ( 1,456,737.00 LBP )
● Cost/Day: 7283686,5 LBP ( 7,283,686.00 LBP )
● Cost/Month: 218510595 LBP ( 218,510,595.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 15,4849 EUR ( 1,453,140.00 LBP )
● Cost/Day: 77,42 EUR ( 7,459,452.00 LBP )
● Cost/Month: 2322,6 EUR ( 224,946,072.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 379,8416 CZK ( 1,447,401.00 LBP )
● Cost/Day: 1899,21 CZK ( 7,252,281.00 LBP )
● Cost/Month: 56976,3 CZK ( 217,591,344.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 168,407 SEK ( 1,412,544.00 LBP )
● Cost/Day: 842,04 SEK ( 7,079,536.00 LBP )
● Cost/Month: 25261,2 SEK ( 212,394,488.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 11,49 GBP ( 1,250,139.00 LBP )
● Cost/Day: 57,45 GBP ( 6,477,993.00 LBP )
● Cost/Month: 1723,5 GBP ( 195,817,227.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 154,0843 NOK ( 1,248,016.00 LBP )
● Cost/Day: 770,42 NOK ( 6,240,080.00 LBP )
● Cost/Month: 23112,6 NOK ( 187,299,648.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 85,9429 EGP ( 155,125.00 LBP )
● Cost/Day: 429,71 EGP ( 782,925.00 LBP )
● Cost/Month: 12891,3 EGP ( 23,526,075.00 LBP )
Breast cancer : (Adults)
● Cost/Unit: 56,7777 TRY ( 150,080.00 LBP )
● Cost/Day: 283,89 TRY ( 758,440.00 LBP )
● Cost/Month: 8516,7 TRY ( 22,822,880.00 LBP )
Prices are provided in Dollar ($)
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